PEMFİGUS

Foreskin (epidermis), bullae (fluid-filled sacs) in the formation of a group of emerging skin disease called pemphigus. PEMF-gusta death, a disease which used to heavy ratio was 100 percent.
REASONS
Cause of pemphigus is not known. In recent years, the virus is thought to be derived. According to this hypothesis the virus, cells in the foreskin lead to disturbances between the cytoplasm after-effects of the disease-causing loses, but this time özbağışıkhk mechanisms activated complex leads to disease progression.
EVIDENCE
The most frequent clinical form of pemphigus vulgaris (common pemphigus) or bullous pemfigustur. Occur at any age, but more often begins between the ages of 40-60. In general, the mucosa of the oral cavity, anus area and painful sexual organs in the region, is characterized by fluid-filled blisters. General situation in the next stage gradually deteriorates. Bullae, especially skin folds (groin, armpit and neck region) where there tends to concentrate. You can be different from the size of bullae. Previously clear liquid in them-truck. Thanks to the blistering skin diseases clinically distinctive property specialist can easily diagnose. With bullae of Pemphigus and no inflammatory changes seen on normal skin. In most cases, a solid blister the skin near the finger-pressed, is a departure from the prepuce. This is the distinctive nature of disease-specific symptom of Nikolsky. This symptom normally found in the foreskin cells indicates that the connection has been corrupted. Spiny cells in the foreskin is attached firmly to each other bridges. This is called the spinous layer. First, this disorder occurs in pemphigus spiny connections. This is called acantholysis. Acantholysis foreskin because of the resulting slits occur in the blisters. Thus, large regions epitelsiz occur. Serous-purulent serum leaking out over the regions covered with shells. Settling of bacteria in the heavy shells embedded in the bullae complications görülür.Üstderi provides differential diagnosis. German side of the bulla base blunt scalpel carved slowly in a flat spread cells, locate tile mosaic of cells that make up the sequence of the foreskin is preserved. Widely applied in this test "Tzanck test" is called. Duhring disease, especially in the differential diagnosis of pemphigus are used to like him.
There is no pain and itching of Pemphigus. Weight loss, fatigue, anorexia, nutritional deficiencies are due to lesions in the mouth. Low levels of protein and albumin in the blood.
After Bullous vegetating form (cauliflower view) form can occur. Sometimes the disease begins to format directly vegetating. Vegetating type, bullous form than the benign. In areas where the skin folds (armpits, groin) is observed. Cracked, bleeding and foul-smelling main feature of the lesions, and receive bristling cauliflower appearance.
Cauliflower-shaped lesions spontaneously or after a period of time will be broken as a result of treatment and disappear, leaving dark spots on the skin. Kaşmtı type and may be a burning sensation and vegetating. Very painful lesions in the mouth. - In a form of pemphigus pemphigus third foliaceus'tar (leaf-shaped pemphigus). This form is uncommon and that covers all the skin, large, loose structure, the blisters occur that tend to coalesce. Peel the skin peeled back, exposing the blisters constantly gives such a view.
A rare type of pemphigus "Senear Usher pemphigus" or "placebo-Reik pemphigus'" tour. There are also trending acute febrile and fatal types of pemphigus.
DIAGNOSIS
Immunological techniques in the diagnosis of pemphigus are fluorine-sans. Connections between cells in the blood of antibodies against Üstde-in subsequent determination of the formation of fully placed. ,
EXPECTED DEPARTURE (Prognosis)

Despite the significant advances in treatment in recent years, often severe. Still, the number of cases decreased durdurulamadığı progress. * An appropriate treatment and recovery time increases survival ste-roitlerin sağlanmaktadır.Pemfigus derivative based on the use of cortisone treatment. Today, the preventive treatment with antibiotics and facilitation of the use of corticosteroids, increased survival of patients with pemphigus. But pemphigus is a severe illness, and always should be remembered that a rigorous monitoring of specialized centers.